Boneset - Eupatorium perfoliatum was an important herb in the traditional medicine of native Americans and it was used for fevers, digestive disorders, rheumatism, as a powerful emetic and laxative. In the Boneset, infusions had a sprinkle of magical protective properties to keep evil spirits away. The name Boneset has nothing to do with its ability to mend bone fractures but refers to its efficacy in treating "break-bone fever", a virulent flu-like illness, from which early settlers suffered. (Houdret 2002). By the eighteenth and nineteenth centuries, European settlers considered boneset to be a cure-all of different diseases. Boneset was used during that time period to treat many different diseases and conditions. It was one of the most widely used herbal medicines in the America. Some families, as well as medical doctors, kept dried boneset available for immediate use, especially during the flu and cold season. Boneset ability to helps reduce fever by promoting sweating, reduces aches and pains, and relieves congestion by loosening phlegm and promoting coughing. Boneset would also stimulate the immune system, which further the destruction of the flu. (Fundukian 2009)
Boneset (Eupatorium perfoliatum) is a common perennial plant that is native to the eastern United States and Canada. The other names for boneset are feverwort, sweat plant, and thoroughwort. The Native American translation name for boneset is ague-weed (ague is the name for malarial fever). The medical constituents that are in Boneset are: sesquiterpene lactones (euccannabinolide, eufoliatin, eufoliatorin, eupafolin, euperfolide, euperfolitin, and helenalin), polysaccharides (4-0-methylglucuroxylans),flavonoids (astragalin, eupatorin, hyperoside, kaempferol, quercitin, rutin, etc.), diterpenes (dendroidinic acid and hebenolide), sterols, volatile oil, tannic acid, resin and gum. (Fundukian 2009)
The abstract on Eupatorium perfoliatum demonstrates that the anti-inflammatory effects caused by the ethanolic extracts can be correlated well with clinical symptoms related to diseases as common cold, rheumatism, arthritis etc. These data also support the credibility of the plant's traditional use by the North American Indians and early European settlers. In principle quality aspects of the Boneset herbal material, it will have to be affirmed by establishing modern pharmacopoeia control methods to guarantee constant and reliable quality. (Hensel, 2011).